“China Health Statistics Yearbook 2019” published by National Health Commission stated that 29.3% patients with foodborne diseases were infected by microorganisms. However, there are often a large number of pathogenic microorganisms such as bacteria and fungi in the nosocomial environment that may injure patients secondly due to microbial infection, which sometimes even results in serious complications like sepsis and induces high morbidity and mortality. Various medical devices, such as intravascular catheters, heart valves, orthopedic implants, dental implants, and contact lenses are often used clinically to treat diseases ( Francolini et al., 2015). ![]() The information will provide a valuable reference to design and develop antibacterial devices that are resistant to pathogenic infections. Their applications and advances in medical device surface coating were also reviewed. This article reviews the mechanism and advantages of antimicrobial polymers and the consideration for their translation. Antibacterial polymers have attracted the interests of researchers due to their unique bactericidal mechanism and excellent antibacterial effect. Therefore, it is urgent to develop new antibacterial drugs to meet clinical or civilian needs. Due to the increasing resistance of pathogens to antibiotics, the efficacy of traditional antibiotics treatment is gradually decreasing for the infection treatment. Medical device contamination caused by microbial pathogens such as bacteria and fungi has posed a severe threat to the patients’ health in hospitals. 4Ningbo Baoting Biotechnology Co., Ltd., Ningbo, China.3Faculty of Materials Science and Chemical Engineering, Ningbo University, Ningbo, China. ![]()
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